Genomic characterization and evolution of Tacaiuma orthobunyavirus (Peribunyaviridae family) isolated in Brazil.

Autor: de Melo AB Junior; Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Ministry of Health, Ananindeua, Pará, Brazil., de Souza WM; Virology Research Center, School of Medicine of Ribeirão Preto of University of São Paulo, Ribeirão Preto, SP, Brazil. Electronic address: wmarciel@usp.br., Acrani GO; Universidade Federal da Fronteira Sul, Passo Fundo, Rio Grande do Sul, Brazil., Carvalho VL; Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Ministry of Health, Ananindeua, Pará, Brazil., Romeiro MF; Virology Research Center, School of Medicine of Ribeirão Preto of University of São Paulo, Ribeirão Preto, SP, Brazil., Tolardo AL; Virology Research Center, School of Medicine of Ribeirão Preto of University of São Paulo, Ribeirão Preto, SP, Brazil., da Silva SP; Center for Technological Innovations, Evandro Chagas Institute, Ministry of Health, Ananindeua, Pará, Brazil., Cardoso JF; Center for Technological Innovations, Evandro Chagas Institute, Ministry of Health, Ananindeua, Pará, Brazil., de Oliveira Chiang J; Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Ministry of Health, Ananindeua, Pará, Brazil., da Silva Gonçalves Vianez JL Júnior; Center for Technological Innovations, Evandro Chagas Institute, Ministry of Health, Ananindeua, Pará, Brazil., do Socorro da Silva Azevedo R; Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Ministry of Health, Ananindeua, Pará, Brazil., Figueiredo LTM; Virology Research Center, School of Medicine of Ribeirão Preto of University of São Paulo, Ribeirão Preto, SP, Brazil., da Costa Vasconcelos PF; Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Ministry of Health, Ananindeua, Pará, Brazil., Nunes MRT; Center for Technological Innovations, Evandro Chagas Institute, Ministry of Health, Ananindeua, Pará, Brazil., de Almeida Medeiros DB; Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Ministry of Health, Ananindeua, Pará, Brazil. Electronic address: danielemedeiros@iec.pa.gov.br.
Jazyk: angličtina
Zdroj: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [Infect Genet Evol] 2018 Jun; Vol. 60, pp. 71-76. Date of Electronic Publication: 2018 Feb 21.
DOI: 10.1016/j.meegid.2018.02.027
Abstrakt: Tacaiuma virus (TCMV) is antigenically characterized as a member of the Anopheles A complex in the Orthobunyavirus genus, Peribunyaviridae family (Bunyavirales order). Clinically, the TCMV infection is characterized by acute febrile illness with myalgia and arthralgia lasting three to five days. However, the genomic and evolutionary aspect of this virus has not been elucidated. In this study, we described the complete coding sequences of three segments of two TCMV strains isolated in Brazil and three complete coding sequences of the small segment of three TCMV strains. All the strains sequenced in this study showed the typical genomic organization of orthobunyaviruses that infect vertebrates, except for the absence of the open reading frame that encodes the well-described non-structural small protein. This study presents the genomic and evolutionary characterization of TCMV strains and would be helpful for diagnostic purposes and epidemiology.
(Copyright © 2018 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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