A preliminary exploration of the potential of Eugenia uvalha Cambess juice intake to counter oxidative stress.

Autor: Lopes JMM; Research Center in Biological Sciences (NUPEB), Federal University of Ouro Preto, Ouro Preto, MG, Brazil; School of Nutrition, Federal University of Ouro Preto, Ouro Preto, MG, Brazil. Electronic address: julianamml@hotmail.com., Lage NN; Research Center in Biological Sciences (NUPEB), Federal University of Ouro Preto, Ouro Preto, MG, Brazil; School of Nutrition, Federal University of Ouro Preto, Ouro Preto, MG, Brazil., Guerra JFC; Institute of Genetics and Biochemistry (INGEB), Federal University of Uberlândia, Patos de Minas Campus, Patos de Minas, MG, Brazil., Silva M; Department of Basic Health, Federal University of Juiz de Fora, Governador Valadares Campus, Governador Valadares, MG, Brazil., Bonomo LF; Department Department of Pharmacy, Federal University of Juiz de Fora, Governador Valadares Campus, Governador Valadares, MG, Brazil., Paulino AHS; Research Center in Biological Sciences (NUPEB), Federal University of Ouro Preto, Ouro Preto, MG, Brazil; School of Nutrition, Federal University of Ouro Preto, Ouro Preto, MG, Brazil., Regis ALRS; School of Nutrition, Federal University of Ouro Preto, Ouro Preto, MG, Brazil., Pedrosa ML; Research Center in Biological Sciences (NUPEB), Federal University of Ouro Preto, Ouro Preto, MG, Brazil; Department of Biological Sciences (DECBI), Federal University of Ouro Preto, Ouro Preto, Brazil., Silva ME; Research Center in Biological Sciences (NUPEB), Federal University of Ouro Preto, Ouro Preto, MG, Brazil; Department of Foods (DEALI), Federal University of Ouro Preto, Ouro Preto, Minas Gerais, Brazil.
Jazyk: angličtina
Zdroj: Food research international (Ottawa, Ont.) [Food Res Int] 2018 Mar; Vol. 105, pp. 563-569. Date of Electronic Publication: 2017 Nov 29.
DOI: 10.1016/j.foodres.2017.11.067
Abstrakt: Purpose: The ability of foods to aid in the prevention of chronic metabolic diseases, has recently become an area of increased interest. In addition, there is growing interest in exploring the benefits of consuming underutilized fruits as alternatives to commercially available fruits. Eugenia uvalha Cambess (uvaia) is a native fruit of Brazil with great market and phytotherapy potential. The present study was conducted to investigate the effects of uvaia juice (UJ) on the levels of protein carbonyls (PCO) and antioxidant enzymes in the livers of rats fed a high-fat diet.
Methods: Thirty-two female rats were randomly assigned to four groups. The rats were fed either a standard diet (group C) or a high-fat diet (group HF). In addition, groups CUJ and HFUJ were treated with UJ (2mL/day) administered via gavage for 8weeks.
Results: In our study, UJ displayed high antioxidant activity (135.14±9.74 GAE/100g). Administration of UJ caused a significantly reduced concentration of rat liver PCO (47.4%), which was associated with a 29% increase in catalase activity. A significant increase in the concentration of oxidized glutathione (GSSG) (15.04±5.08nmol/ml) and a reduction in the reduced glutathione/oxidized glutathione ratio (GSH/GSSG) (11.30±2.68) were found in the HF group, whilst these changes were not observed in the HFUJ group (a result similar to that of group C).
Conclusions: Our results demonstrate that UJ decreases oxidative damage by improving antioxidant efficiency and attenuating oxidative damage to proteins.
(Copyright © 2017 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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