Efficacy of a Structured Exercise Program for Improving Functional Capacity and Quality of Life in Patients With Stage 3 and 4 Sarcoidosis: A RANDOMIZED CONTROLLED TRIAL.
| Autor: | Naz I; Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Izmir Katip Celebi University, Izmir, Turkey (Dr Naz), Dokuz Eylul University, School of Physical Therapy and Rehabilitation, Izmir, Turkey (Dr Ozalevli); and Dr Suat Seren Chest Disease and Thoracic Surgery Training and Research Hospital, Izmir, Turkey (Drs Ozkan and Sahin)., Ozalevli S, Ozkan S, Sahin H |
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| Jazyk: | angličtina |
| Zdroj: | Journal of cardiopulmonary rehabilitation and prevention [J Cardiopulm Rehabil Prev] 2018 Mar; Vol. 38 (2), pp. 124-130. |
| DOI: | 10.1097/HCR.0000000000000307 |
| Abstrakt: | Purpose: This study investigated the effects of an exercise program on functional capacity and quality of life in patients with stage 3 and stage 4 sarcoidosis. Methods: Eighteen patients with stage 3 and 4 sarcoidosis were recruited; 9 received 12 wk of supervised exercise training and 9 received usual care. Patients underwent the following evaluations at baseline and follow-up: 6-min walk test, maximal inspiratory and expiratory pressure tests, back and leg dynamometer test, modified Medical Research Council Dyspnea Scale, Fatigue Severity Scale, St George Respiratory Questionnaire, Short Form-36 Quality of Life Questionnaire, Hospital Anxiety and Depression Questionnaire, body plethysmography, carbon monoxide diffusing capacity test, and blood gas analysis. Results: The median (interquartile range) increase in 6-min walk distance in the intervention group was 40 (31-62) m. Improvement in functional capacity; perception of dyspnea; fatigue; anxiety; peripheral and inspiratory muscle strength; partial arterial oxygen pressure; arterial oxygen saturation; and the symptom, activity, and total scores of the St George Respiratory Questionnaire were significantly greater in the intervention group than in the usual care group at follow-up (P < .05). Conclusions: Exercise training improves functional capacity, muscle strength, dyspnea, quality of life, anxiety, fatigue, and oxygenation in patients with stage 3 and stage 4 sarcoidosis. Standard treatment of patients with late-stage sarcoidosis should integrate exercise training and pulmonary rehabilitation. |
| Databáze: | MEDLINE |
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