Coffee, tea and caffeine consumption and risk of primary infertility in women: a Danish cohort study.

Autor:	Í Soylu L; Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark., Jensen A; Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark., Juul KE; Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark., Kesmodel US; Department of Obstetrics and Gynecology, Herlev Hospital, Herlev, Denmark., Frederiksen K; Statistics, Bioinformatics and Registry, Danish Cancer Society Research Center, Copenhagen, Denmark., Kjaer SK; Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark.; Department of Gynecology, Rigshospitalet University Hospital, Copenhagen, Denmark., Hargreave M; Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark.
Jazyk:	angličtina
Zdroj:	Acta obstetricia et gynecologica Scandinavica [Acta Obstet Gynecol Scand] 2018 May; Vol. 97 (5), pp. 570-576. Date of Electronic Publication: 2018 Feb 22.
DOI:	10.1111/aogs.13307
Abstrakt:	Introduction: The aim of this study was to investigate whether consumption of coffee, tea and caffeine affects the risk of primary infertility in women. Material and Methods: We selected nulliparous Danish women aged 20-29 years from a prospective cohort and retrieved information on coffee and tea consumption from a questionnaire and an interview at enrollment. We assessed the women's fertility by linkage to the Danish Infertility Cohort and retrieved information on children and vital status from the Civil Registration System. All 7574 women included for analysis were followed for primary infertility from the date of enrollment (1991-1993) until 31 December 2010. Analyses were performed with Cox proportional hazard models. Results: During follow up, primary infertility was diagnosed in 822 women. Compared with never consumers, the risk of primary infertility among women who drank coffee or tea was not affected. The risk of primary infertility was neither associated with an increasing number of daily servings of coffee (hazard ratio 1.00; 95% confidence interval (CI), 0.97-1.03) or tea (hazard ratio 1.01; 95% CI, 0.99-1.03) in consumers only. Concerning total caffeine consumption (from coffee and tea), the risk of infertility was similar among consumers compared with never consumers. Finally, none of the additional daily 100 mg of caffeine affected the risk among consumers only (hazard ratio 1.00; 95% CI 0.98-1.02). Conclusions: In this population-based cohort study, not restricted to women seeking pregnancy, we found no association between coffee, tea or total caffeine consumption and the risk of primary infertility in women. (© 2018 Nordic Federation of Societies of Obstetrics and Gynecology.)
Databáze:	MEDLINE
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