| Autor: |
Gerbaba TK; Department of Medicine, Queen's University, Kingston, ON, Canada., Green-Harrison L; Department of Biological Sciences, University of Calgary, Calgary, AB, Canada., Buret AG; Department of Biological Sciences, University of Calgary, Calgary, AB, Canada. |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of nematology [J Nematol] 2017 Dec; Vol. 49 (4), pp. 348-356. |
| Abstrakt: |
The microbiome influences host processes including nutritional availability, development, immunity, and behavioral responses. Caenorhabditis elegans is a powerful model to study molecular mechanisms of host-microbial interactions. Recent efforts have been made to profile the natural microbiome of C. elegans , laying a foundation for mechanistic studies of host-microbiome interactions in this genetically tractable model system. Studies using single-species microbes, multi-microbial systems, and humanized worm-microbiome interaction studies reveal metabolic and microbial-microbial interactions relevant in higher organisms. This article discusses recent developments in modeling the effects of host-microbiome interactions in C. elegans . |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
