| Autor: |
Braun JM; Department of Epidemiology, Brown University, Providence, Rhode Island, United States of America., Gray K; National Institute of Environmental Health Sciences, Durham, North Carolina, United States of America. |
| Jazyk: |
angličtina |
| Zdroj: |
PLoS biology [PLoS Biol] 2017 Dec 19; Vol. 15 (12), pp. e2002800. Date of Electronic Publication: 2017 Dec 19 (Print Publication: 2017). |
| DOI: |
10.1371/journal.pbio.2002800 |
| Abstrakt: |
Epidemiological studies play an important role in quantifying how early life environmental chemical exposures influence the risk of childhood diseases. These studies face at least four major challenges that can produce noise when trying to identify signals of associations between chemical exposure and childhood health. Challenges include accurately estimating chemical exposure, confounding from causes of both exposure and disease, identifying periods of heightened vulnerability to chemical exposures, and determining the effects of chemical mixtures. We provide recommendations that will aid in identifying these signals with more precision. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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