Depressive symptoms and cognitive deficits in a cancer patient submitted to chemotherapy with 5-Fluoracil: a case report.
| Autor: | Bottino SMB; Department of Psychiatry, Federal University of São Paulo., Garcia CPG; Old Age Research Group, Institute of Psychiatry, University of São Paulo., Viana BM; Old Age Research Group, Institute of Psychiatry, University of São Paulo., Bottino CMC; Old Age Research Group, Institute of Psychiatry, University of São Paulo. |
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| Jazyk: | angličtina |
| Zdroj: | Dementia & neuropsychologia [Dement Neuropsychol] 2013 Jul-Sep; Vol. 7 (3), pp. 308-311. |
| DOI: | 10.1590/S1980-57642013DN70300013 |
| Abstrakt: | Cognitive deficits in cancer patients can be related to depression, anxiety, and the side effects of treatments such as fatigue. In this case report, we described an elderly patient with rectal adenocarcinoma, which presented depressive symptoms and memory complaints after treatment with 5-Fluoracil and Leucovorin. Depressive symptoms improved after two months but cognitive and functional impairment worsened suggesting the diagnosis of mild dementia. Structural and functional brain changes were seen on neuroimaging exams. Rivastigmine was introduced up to 12 mg/day, and after a one-year follow up the patient remained stable. Cognitive deficits can be a consequence of cancer therapies and a protocol to investigate deficits cognitive could be useful to the diferential diagnosis and management of elderly cancer patients submitted to chemotherapy. Competing Interests: Disclosure: The authors report no conflicts of interest. |
| Databáze: | MEDLINE |
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