Autor: |
Wang ZF; Department of Radiology, the Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Hospital of Zhejiang University, Lishui 323000, China., Lan XL, Xiao YR, Liu JP, Ji JS |
Jazyk: |
čínština |
Zdroj: |
Zhonghua yi xue za zhi [Zhonghua Yi Xue Za Zhi] 2017 Oct 24; Vol. 97 (39), pp. 3104-3107. |
DOI: |
10.3760/cma.j.issn.0376-2491.2017.39.013 |
Abstrakt: |
Objective: To investigate the correlation between TNM staging of primary cholangiocarcinoma and the maximum standard uptake value (SUVmax) of (18)F-2-deoxy-D-glucose positron emission tomography with computerized tomography ((18)F-FDG PET/CT). Methods: A retrospective analysis of 36 patients with confirmed primary cholangiocarcinoma from October 2014 to July 2016 was carried out. All the patients underwent preoperative PET/CT in the Fifth Affiliated Hospital of Wenzhou Medical University from November 2014 to July 2016, the SUVmax was calculated by drawing region of interest around the primitive tumor area.According to the American Cancer Joint Committee (AJCC) guidelines for the clinical staging of intrahepatic and extrahepatic cholangiocarcinoma, the differences of SUVmax were compared in the patients with different age, gender and staging, and the correlation between TNM staging and SUVmax was determined.Data were compared with independent sample t test between groups. Results: The mean SUVmax of 36 patients with primary cholangiocarcinoma was 7.87±3.17 (2.1-14.6). The SUVmax values of patients with lymph node metastasis or distant metastasis were significantly higher than those without lymph node metastasis or distant metastasis ( t =0.364, 0.343, both P <0.05), respectively. There was significant difference in SUVmax between patients with different TNM staging ( F =1.352, P =0.021). There was no significant differences in SUVmax between patient with different gender, age (>70 years or<70 years) and T staging ( t =1.058, 1.980, F =1.252, all P >0.05). Spearman correlation analyses showed that the TNB stage of primary cholangiocarcinoma was positively correlated with its SUVmax ( r =0.658, P =0.007). Conclusion: The SUVmax is positively correlated with the TNM staging of primary cholangiocarcinoma, which is helpful for the clinical staging and prognosis of the patients. |
Databáze: |
MEDLINE |
Externí odkaz: |
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