α-TCP cements prepared by syringe-foaming: Influence of Na 2 HPO 4 and surfactant concentration.

Autor: Vásquez AF; Biomaterials Laboratory, Department of Materials Engineering, Federal University of Rio Grande do Sul, Porto Alegre, Brazil; GINEWS: New Stetic's Research Group, Department of Research and Development, New Stetic S.A, Guarne, Colombia. Electronic address: afvasquez@newstetic.com., Domínguez S; Department of Chemical Engineering, University of Antioquia, Medellín, Colombia., Loureiro Dos Santos LA; Biomaterials Laboratory, Department of Materials Engineering, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Jazyk: angličtina
Zdroj: Materials science & engineering. C, Materials for biological applications [Mater Sci Eng C Mater Biol Appl] 2017 Dec 01; Vol. 81, pp. 148-155. Date of Electronic Publication: 2017 Aug 01.
DOI: 10.1016/j.msec.2017.07.056
Abstrakt: The lack of intrinsic open porosity in calcium phosphate cements slows down the resorption rate and bone ingrowth when implanted In Vivo. In this study, macroporous structures were obtained by mixing α-TCP cement with a foamed liquid phase containing different concentrations of sodium hydrogen phosphate and a nonionic surfactant. The cement paste was prepared by hand mixing in a novel system of two syringes connected by a tube. Two different liquid to powder (L/P) ratios were used to prepare the cement paste. The cement samples showed open macropores with diameters>100μm. The specimens prepared with lower L/P ratio showed smaller porosity, macroporosity and pore size distribution. The cohesion of the cement paste in liquid solutions was assessed by adding 2wt% sodium alginate to the liquid phase. This study suggests that the final macrostructure of the foamed cements can be controlled by varying the phosphate and surfactant concentrations in the liquid phase and the L/P ratio.
(Copyright © 2017 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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