| Autor: |
Rafferty ER; School of Public Health, University of Saskatchewan, Saskatoon, Saskatchewan, Canada., Schurer JM; Center for One Health Research, University of Washington, Seattle, Washington, United States of America., Arndt MB; PATH, San Francisco, California, United States of America.; Department of Global Health, University of Washington, Seattle, Washington, United States of America., Choy RKM; PATH, San Francisco, California, United States of America., de Hostos EL; PATH, San Francisco, California, United States of America., Shoultz D; PATH, San Francisco, California, United States of America., Farag M; School of Public Health, University of Saskatchewan, Saskatoon, Saskatchewan, Canada. |
| Abstrakt: |
Cryptosporidium is a leading cause of pediatric diarrhea in resource-limited settings; yet, few studies report the health care costs or societal impacts of this protozoan parasite. Our study examined direct and indirect costs associated with symptomatic cryptosporidiosis in infants younger than 12 months in Kenya, Peru and Bangladesh. Inputs to the economic burden model, such as disease incidence, population size, health care seeking behaviour, hospital costs, travel costs, were extracted from peer-reviewed literature, government documents, and internationally validated statistical tools for each country. Indirect losses (i.e. caregiver income loss, mortality, and growth faltering) were also estimated. Our findings suggest that direct treatment costs per symptomatic cryptosporidiosis episode were highest in Kenya ($59.01), followed by Peru ($23.32), and Bangladesh ($7.62). The total annual economic impacts for the 0-11 month cohorts were highest in Peru ($41.5M; range $0.88-$599.3M), followed by Kenya ($37.4M; range $1.6-$804.5M) and Bangladesh ($9.6M, range $0.28-$91.5M). For all scenarios, indirect societal costs far outweighed direct treatment costs. These results highlight the critical need for innovative improvements to current prevention, diagnostic and treatment strategies available in resource poor settings, as well as the need for solutions that span multiple disciplines including food and water safety, sanitation and livestock production. |
