The "hook effect" causing a negative pregnancy test in a patient with an advanced molar pregnancy.

Autor: Winder AD; John I. Brewer Trophoblastic Disease Center, Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States., Mora AS; John I. Brewer Trophoblastic Disease Center, Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States., Berry E; John I. Brewer Trophoblastic Disease Center, Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States., Lurain JR; John I. Brewer Trophoblastic Disease Center, Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Jazyk: angličtina
Zdroj: Gynecologic oncology reports [Gynecol Oncol Rep] 2017 Jun 07; Vol. 21, pp. 34-36. Date of Electronic Publication: 2017 Jun 07 (Print Publication: 2017).
DOI: 10.1016/j.gore.2017.06.008
Abstrakt: •At high hCG levels in molar pregnancies, a "hook effect" can cause an artificially negative value.•Delay in diagnosis of a molar pregnancy due to the "hook effect" can lead to severe complications.•Suspicion of a molar pregnancy should be communicated so a diluted sample is used to quantify hCG.
Databáze: MEDLINE