| Autor: |
Zherdev VP, Martynova LA, Caccia S, Garattini S, Ekonomov AL |
| Jazyk: |
ruština |
| Zdroj: |
Farmakologiia i toksikologiia [Farmakol Toksikol] 1985 Jan-Feb; Vol. 48 (1), pp. 31-5. |
| Abstrakt: |
It has been established that phenazepam is rapidly absorbed from the gastrointestinal tract of animals and man. The maximal concentrations of the unchanged drugs are reached 1, 0.5, 2 and 4 hours in rats, dogs, cats and man, respectively. The half-life of phenazepam in animal and human blood decreases in the following order: man greater than cat greater than dog greater than rat. The metabolite 3 + hydroxyphenazepam was identified in appreciable amounts in cat and rat blood. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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