[Type of Thrombolytic Agent and Rate of Acute Kidney Injury in Patients With Myocardial Infarction].

Autor:	Menzorov MV; Department of Internal Medicine, Ulyanovsk State University, ul. Architect Livchaka, 2/1, 432063 Ulyanovsk, Russia., Shutov AM; Department of Internal Medicine, Ulyanovsk State University, ul. Architect Livchaka, 2/1, 432063 Ulyanovsk, Russia., Serov VA; Department of Internal Medicine, Ulyanovsk State University, ul. Architect Livchaka, 2/1, 432063 Ulyanovsk, Russia., Saenko YV; Department of Internal Medicine, Ulyanovsk State University, ul. Architect Livchaka, 2/1, 432063 Ulyanovsk, Russia., Grishenkin IY; Department of Internal Medicine, Ulyanovsk State University, ul. Architect Livchaka, 2/1, 432063 Ulyanovsk, Russia.
Jazyk:	ruština
Zdroj:	Kardiologiia [Kardiologiia] 2015 Feb; Vol. 55 (2), pp. 16-20.
Abstrakt:	Aim of this study was to assess incidence and severity of acute kidney injury (AKI) in patients with ST-elevation (STE) myocardial infarction (MI) after thrombolytic therapy with alteplase or streptokinase. Among 292 included patients (227 men, 65 women, mean age 58+/-11 years) 170 received streptokinase, 122 - alteplase. Coronary angiography in acute stage of MI was an exclusion criterion. Thrombolysis was effective in 213 (73%) patients. There was no statistically significant difference in effectiveness of thrombolysis among streptokinase or alteplase treated patients. Incidence of AKI in patients with STEMI was 25%. Both incidence and severity of AKI were higher in streptokinase treated patients. Only stage II-III AKI was significantly associated with higher in-hospital mortality.
Databáze:	MEDLINE
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