A Case Report of the First Nonburn-related Military Trauma Victim Treated with Spray Skin Regenerative Therapy in Combination with a Dermal Regenerate Template.

Autor: Valerio IL; Department of Plastic Surgery, The Ohio State Wexner Medical Center, Columbus, Ohio.; and Departments of Oral and Maxillofacial Surgery, Plastic and Reconstructive Surgery, and Orthopedic Surgery, Walter Reed National Military Medical Center, Bethesda, Md., Hammer DA; Department of Plastic Surgery, The Ohio State Wexner Medical Center, Columbus, Ohio.; and Departments of Oral and Maxillofacial Surgery, Plastic and Reconstructive Surgery, and Orthopedic Surgery, Walter Reed National Military Medical Center, Bethesda, Md., Rendon JL; Department of Plastic Surgery, The Ohio State Wexner Medical Center, Columbus, Ohio.; and Departments of Oral and Maxillofacial Surgery, Plastic and Reconstructive Surgery, and Orthopedic Surgery, Walter Reed National Military Medical Center, Bethesda, Md., Latham KP; Department of Plastic Surgery, The Ohio State Wexner Medical Center, Columbus, Ohio.; and Departments of Oral and Maxillofacial Surgery, Plastic and Reconstructive Surgery, and Orthopedic Surgery, Walter Reed National Military Medical Center, Bethesda, Md., Fleming ME; Department of Plastic Surgery, The Ohio State Wexner Medical Center, Columbus, Ohio.; and Departments of Oral and Maxillofacial Surgery, Plastic and Reconstructive Surgery, and Orthopedic Surgery, Walter Reed National Military Medical Center, Bethesda, Md.
Jazyk: angličtina
Zdroj: Plastic and reconstructive surgery. Global open [Plast Reconstr Surg Glob Open] 2016 Dec 27; Vol. 4 (12), pp. e1174. Date of Electronic Publication: 2016 Dec 27 (Print Publication: 2016).
DOI: 10.1097/GOX.0000000000001174
Abstrakt: Massive soft tissue and skin loss secondary to war-related traumas are among the most frequently encountered challenges in the care of wounded warriors. This case report outlines the first military nonburn-related trauma patient treated by a combination of regenerative modalities. Our case employs spray skin technology to an established dermal regenerate matrix. Our patient, a 29-year-old active duty male, suffered a combat blast trauma in 2010 while deployed. The patient's treatment course was complicated by a severe necrotizing fasciitis infection requiring over 100 surgical procedures for disease control and reconstruction. In secondary delayed reconstruction procedures, this triple-limb amputee underwent successful staged ventral hernia repair via a component separation technique with biologic mesh underlay although this resulted in a skin deficit of more than 600 cm 2 . A dermal regenerate template was applied to the abdominal wound to aid in establishing a "neodermis." Three weeks after dermal regenerate application, spray skin was applied to the defect in conjunction with a 6:1 meshed split thickness skin graft. The dermal regenerate template allowed for optimization of the wound bed for skin grafting. The use of spray skin allowed for a 6:1 mesh ratio, thus minimizing the donor-site size and morbidity. Together, this approach resulted in complete healing of a large full-thickness wound. The patient is now able to perform activities of daily living, walk without a cane, and engage in various physical activities. Overall, our case highlights the potential that combining regenerative therapies can achieve in treating severe war-related and civilian traumatic injuries.
Databáze: MEDLINE