Sequential Growth of NaYF 4 :Yb/Er@NaGdF 4 Nanodumbbells for Dual-Modality Fluorescence and Magnetic Resonance Imaging.

Autor: Wen HQ; Department of Immunology, Department of Pathogen Biology, Provincial Laboratories of Pathogen Biology and Zoonoses Anhui, and Clinical Laboratory of the First Affiliated Hospital, Anhui Medical University , Hefei, Anhui 230022, China.; Department of Blood Transfusion, The First Affiliated Hospital of Anhui Medical University , Hefei, Anhui 230022, China., Peng HY, Liu K, Bian MH; Department of Blood Transfusion, The First Affiliated Hospital of Anhui Medical University , Hefei, Anhui 230022, China., Xu YJ; Department of Radiology, Anhui Provincial Hospital , Hefei, Anhui 230001, China., Dong L, Yan X; Department of Radiology, Anhui Provincial Hospital , Hefei, Anhui 230001, China., Xu WP; Department of Radiology, Anhui Provincial Hospital , Hefei, Anhui 230001, China., Tao W, Shen JL; Department of Immunology, Department of Pathogen Biology, Provincial Laboratories of Pathogen Biology and Zoonoses Anhui, and Clinical Laboratory of the First Affiliated Hospital, Anhui Medical University , Hefei, Anhui 230022, China., Lu Y, Qian HS
Jazyk: angličtina
Zdroj: ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2017 Mar 22; Vol. 9 (11), pp. 9226-9232. Date of Electronic Publication: 2017 Mar 09.
DOI: 10.1021/acsami.6b16842
Abstrakt: Upconversional core-shell nanostructures have gained considerable attention due to their distinct enhanced fluorescence efficiency, multifunctionality, and specific applications. Recently, we have developed a sequential growth process to fabricate unique upconversion core-shell nanoparticles. Time evolution of morphology for the NaYF 4 :Yb/Er@NaGdF 4 nanodumbbells has been extensively investigated. An Ostwald ripening growth mechanism has been proposed to illustrate the formation of NaYF 4 :Yb/Er@NaGdF 4 nanodumbbells. The hydrophilic NaYF 4 :Yb/Er@NaGdF 4 core-shell nanodumbbells exhibited strong upconversion fluorescence and showed higher magnetic resonance longitudinal relaxivity (r 1 = 7.81 mM -1 s -1 ) than commercial contrast agents (Gd-DTPA). NaYF 4 :Yb/Er@NaGdF 4 nanodumbbells can serve as good candidates for high efficiency fluorescence and magnetic resonance imaging.
Databáze: MEDLINE
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