Bell's palsy in children: Current treatment patterns in Australia and New Zealand. A PREDICT study.

Autor: Babl FE; Emergency Department, Royal Children's Hospital, Melbourne, Victoria, Australia.; Clinical Sciences Theme, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Department of Paediatrics, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, Australia., Gardiner KK; Clinical Sciences Theme, Murdoch Children's Research Institute, Melbourne, Victoria, Australia., Kochar A; Emergency Department, Women's and Children's Hospital, Adelaide, South Australia, Australia., Wilson CL; Clinical Sciences Theme, Murdoch Children's Research Institute, Melbourne, Victoria, Australia., George SA; Emergency Department, Gold Coast University Hospital, School of Medicine, Griffith University, Gold Coast, Townsville, Queensland, Australia., Zhang M; Emergency Department, John Hunter Hospital, Newcastle, New South Wales, Australia., Furyk J; Emergency Department, Townsville Hospital and James Cook University College of Medicine and Dentistry, Townsville, Queensland, Australia., Thosar D; Emergency Department, The Children's Hospital at Westmead, Sydney, New South Wales, Australia., Cheek JA; Emergency Department, Royal Children's Hospital, Melbourne, Victoria, Australia.; Clinical Sciences Theme, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.; Emergency Department, Monash Medical Centre, Melbourne, Victoria, Australia., Krieser D; Emergency Department, Sunshine Hospital, Melbourne, Victoria, Australia., Rao AS; Emergency Department, Sydney Children's Hospital, Sydney, New South Wales, Australia., Borland ML; Emergency Department, Princess Margaret Hospital for Children, Perth, Western Australia, Australia.; Schools of Paediatric and Child Health and Primary, Aboriginal and Rural Health Care, University of Western Australia, Perth, Western Australia, Australia., Cheng N; Emergency Department, The Children's Hospital at Westmead, Sydney, New South Wales, Australia., Phillips NT; Emergency Department, Lady Cilento Children's Hospital, Brisbane, Queensland, Australia., Sinn KK; Emergency Department, Canberra Hospital, Canberra, Australian Capital Territory, Australia., Neutze JM; Emergency Department, KidzFirst Middlemore Hospital, Auckland, New Zealand.; Liggins Institute, University of Auckland, Auckland, New Zealand., Dalziel SR; Liggins Institute, University of Auckland, Auckland, New Zealand.; Emergency Department, Starship Children's Hospital, Auckland, New Zealand.
Jazyk: angličtina
Zdroj: Journal of paediatrics and child health [J Paediatr Child Health] 2017 Apr; Vol. 53 (4), pp. 339-342. Date of Electronic Publication: 2017 Feb 08.
DOI: 10.1111/jpc.13463
Abstrakt: Aim: The aetiology and clinical course of Bell's palsy may be different in paediatric and adult patients. There is no randomised placebo controlled trial (RCT) to show effectiveness of prednisolone for Bell's palsy in children. The aim of the study was to assess current practice in paediatric Bell's palsy in Australia and New Zealand Emergency Departments (ED) and determine the feasibility of conducting a multicentre RCT within the Paediatric Research in Emergency Departments International Collaborative (PREDICT).
Methods: A retrospective analysis of ED medical records of children less than 18 years diagnosed with Bell's palsy between 1 January, 2012 and 31 December, 2013 was performed. Potential participants were identified from ED information systems using Bell's palsy related search terms. Repeat presentations during the same illness were excluded but relapses were not. Data on presentation, diagnosis and management were entered into an online data base (REDCap).
Results: Three hundred and twenty-three presentations were included from 14 PREDICT sites. Mean age at presentation was 9.0 (SD 5.0) years with 184 (57.0%) females. Most (238, 73.7%) presented to ED within 72 h of symptoms, 168 (52.0%) had seen a doctor prior. In ED, 218 (67.5%) were treated with steroids. Prednisolone was usually prescribed for 9 days at around 1 mg/kg/day, with tapering in 35.7%.
Conclusion: Treatment of Bell's palsy in children presenting to Australasian EDs is varied. Prednisolone is commonly used in Australasian EDs, despite lack of high-level paediatric evidence. The study findings confirm the feasibility of an RCT of prednisolone for Bell's palsy in children.
(© 2017 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).)
Databáze: MEDLINE
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