Indium triflate catalysed 3-aza-Cope rearrangement of amino acid derived α,β-unsaturated esters to alkylidene oxindoles.

Autor: Kumar MS; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, BS 10/1, Sector 10, Jankipuram extension, Sitapur Road, Lucknow 226031, India., Manna SK; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, BS 10/1, Sector 10, Jankipuram extension, Sitapur Road, Lucknow 226031, India., Maji S; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, BS 10/1, Sector 10, Jankipuram extension, Sitapur Road, Lucknow 226031, India., Panda G; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, BS 10/1, Sector 10, Jankipuram extension, Sitapur Road, Lucknow 226031, India and Academy of Scientific and Innovative Research, New Delhi 110001, India. gautam_panda@cdri.res.in gautam.panda@gmail.com.
Jazyk: angličtina
Zdroj: Organic & biomolecular chemistry [Org Biomol Chem] 2017 Feb 22; Vol. 15 (8), pp. 1762-1766.
DOI: 10.1039/c6ob02419j
Abstrakt: The first examples of amino acid derived α,β-unsaturated esters to Z-alkylidene oxindoles via 3-aza-Cope rearrangement using In(OTf) 3 are reported.
Databáze: MEDLINE