Macular Thickness Assessment in Patients with Glaucoma and Its Correlation with Visual Fields.

Autor:	Mota M; Resident, Department of Ophthalmology, Prof. Doutor Fernando Fonseca Hospital, Lisbon, Portugal., Vaz FT; Ophthalmologist, Department of Ophthalmology, Prof. Doutor Fernando Fonseca Hospital, Lisbon, Portugal., Ramalho M; Ophthalmologist, Department of Ophthalmology, Prof. Doutor Fernando Fonseca Hospital, Lisbon, Portugal., Pedrosa C; Resident, Department of Ophthalmology, Prof. Doutor Fernando Fonseca Hospital, Lisbon, Portugal., Lisboa M; Ophthalmologist, Department of Ophthalmology, Prof. Doutor Fernando Fonseca Hospital, Lisbon, Portugal., Kaku P; Ophthalmologist, Department of Ophthalmology, Prof. Doutor Fernando Fonseca Hospital, Lisbon, Portugal., Esperancinha F; Ophthalmologist, Department of Ophthalmology, Prof. Doutor Fernando Fonseca Hospital, Lisbon, Portugal.
Jazyk:	angličtina
Zdroj:	Journal of current glaucoma practice [J Curr Glaucoma Pract] 2016 Sep-Dec; Vol. 10 (3), pp. 85-90. Date of Electronic Publication: 2016 Oct 29.
DOI:	10.5005/jp-journals-10008-1207
Abstrakt:	Aim: To determine the relationship between macular thickness (MT) and visual field (VF) parameters, as well as with changes in the retinal nerve fiber layer (RNFL) thickness in patients with glaucoma and ocular hypertension (OH). Materials and Methods: Cross-sectional statistical analysis of spectral domain optical coherence tomography (SD-OCT) compared with several VF parameters (mean defect - MD and loss variance - LV), in a nonrandom sample of 70 eyes from patients with glaucoma or OH. Statistical analysis was performed using Statistical Package for Social Sciences ® . The correlation coefficient used was determined by Spearman correlation and the value of p < 0.05 was considered statistically significant. Results: A significant correlation was seen between VF parameters and decrease in MT (MD: r = -0.363, p = 0.002; LV: r=-0.378, p = 0.001). The results were more significant when we compared the LV in the group with average MT 270 to 300 μm (r = -0.413, p = 0.015). Asymmetry between the superior macula and inferior macula correlated with LV (r = 0.432, p = 0.019) in the group with MT < 270 μm. There was also a significant correlation between thinning of superior-temporal and inferior-temporal RNFL and the decrease of the superior and inferior MT respectively (p < 0.001). Conclusion: Spectral domain optical coherence tomography measurements of retinal thickness in the macula correlate with VF parameters and RNFL parameters in glaucoma patients. This relationship was first demonstrated with static computerized perimetry made with Octopus 101 ® . These results can be a valuable aid for evaluating and monitoring of glaucoma patients, establishing a correlation between structure and function. Measurements of retinal thickness in the macula may be an additional instrument for early detection of structural changes and its correlation with functional defects. How to Cite This Article: Mota M, Vaz FT, Ramalho M, Pedrosa C, Lisboa M, Kaku P, Esperancinha F. Macular Thickness Assessment in Patients with Glaucoma and Its Correlation with Visual Fields. J Curr Glaucoma Pract 2016;10(3):85-90. Competing Interests: Source of support: Nil Conflict of interest: None
Databáze:	MEDLINE
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