| Autor: |
Ovais M; Department of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan., Khalil AT; Department of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan., Raza A; National Institute for Lasers & Optronics, Pakistan Atomic Energy Commission, Islamabad, Pakistan., Khan MA; Department of Zoology, University of Azad Jammu & Kashmir, Muzaffarabad, Pakistan., Ahmad I; Department of Life sciences, King Fahd University of Petroleum & Minerals, Dhahran, Saudi Arabia., Islam NU; Department of Pharmacy, Sarhad University of Science & Information Technology, Peshawar, Pakistan., Saravanan M; Department of Medical Microbiology & Immunology, Institute of Biomedical Sciences, College of Health Sciences, Mekelle University, Mekelle, Ethiopia., Ubaid MF; Azad Jammu & Kashmir Medical College, Muzaffarabad, Pakistan., Ali M; Department of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan., Shinwari ZK; Department of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan.; Pakistan Academy of Sciences, Islamabad, Pakistan. |
| Abstrakt: |
With the development of the latest technologies, scientists are looking to design novel strategies for the treatment and diagnosis of cancer. Advances in medicinal plant research and nanotechnology have attracted many researchers to the green synthesis of metallic nanoparticles due to its several advantages over conventional synthesis (simple, fast, energy efficient, one pot processes, safer, economical and biocompatibility). Medicinally active plants have proven to be the best reservoirs of diverse phytochemicals for the synthesis of biogenic silver nanoparticles (AgNPs). In this review, we discuss mechanistic advances in the synthesis and optimization of AgNPs from plant extracts. Moreover, we have thoroughly discussed the recent developments and milestones achieved in the use of biogenic AgNPs as cancer theranostic agents and their proposed mechanism of action. Anticipating all of the challenges, we hope that biogenic AgNPs may become a potential cancer theranostic agent in the near future. |
