[Types of immune response in advanced suppurative peritonitis].

Autor: Borisov AG; Research Institute of Medical Problems of the North, Krasnoyarsk., Savchenko AA; Research Institute of Medical Problems of the North, Krasnoyarsk; Voyno-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk., Cherdantsev DV; Voyno-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk; Regional Clinical Hospital, Krasnoyarsk., Zdzitovetsky DE; Voyno-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk., Pervova OV; Voyno-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk., Kudryavtsev IV; Research Institute of Experimental Medicine, St. Petersburg; Far Eastern Federal University, Vladivostok, Russia., Belenyuk VD; Research Institute of Medical Problems of the North, Krasnoyarsk., Shapkina VA; Voyno-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk.
Jazyk: ruština
Zdroj: Khirurgiia [Khirurgiia (Mosk)] 2016 (9), pp. 28-34.
DOI: 10.17116/hirurgia2016928-34
Abstrakt: Aim: to assess types of immune response in patients with advanced suppurative peritonitis and course of disease.
Material and Methods: We examined 79 patients with acute surgical abdominal diseases and injuries complicated by advanced suppurative peritonitis. Blood immunological parameters were estimated using flowing cytometry and enzyme immunoassay.
Results: It was concluded that functional parameters of immune system are very various in patients with advanced suppurative peritonitis. Cluster analysis defined 4 immune types which are determined by different state of congenital and acquired immunity. Immunodeficient and unreactive immune types are unfavorable. Immune types with activation of congenital and acquired immunity are the most favourable. This stratification personifies diagnosis and treatment of immune disorders in patients with advanced suppurative peritonitis.
Databáze: MEDLINE