[Patterns of ocular neurovascular reactions].

Autor:	Lazarenko VI; Krasnoyarsk State Medical University named after prof. V.F. Voyno-Yasenetsky, 1 Partizana Zeleznyaka St., Krasnoyarsk, Russian Federation, 660022., Kadantseva AS; Krasnoyarsk regional ophthalmological clinical hospital named after prof. P.G. Makarov, 1v Nikitina St., Krasnoyarsk, Russian Federation, 660022., Savchenkov YI; Krasnoyarsk State Medical University named after prof. V.F. Voyno-Yasenetsky, 1 Partizana Zeleznyaka St., Krasnoyarsk, Russian Federation, 660022., Shatilova RI; Krasnoyarsk State Medical University named after prof. V.F. Voyno-Yasenetsky, 1 Partizana Zeleznyaka St., Krasnoyarsk, Russian Federation, 660022.
Jazyk:	ruština
Zdroj:	Vestnik oftalmologii [Vestn Oftalmol] 2016 May-Jun; Vol. 132 (3), pp. 26-31.
DOI:	10.17116/oftalma2016132326-31
Abstrakt:	Aim: To examine factors and determinants of ocular neurovascular reactions (NVR). Material and Methods: The study included 120 healthy participants of both sexes aged 20.9±0.6 years, who underwent a standard ophthalmic examination. Ocular microcirculation was recorded using laser Doppler flowmetry. Autonomic homeostasis and the intensity of slow-wave oscillations of hemodynamics were of interest. Autoregulation of cerebral blood flow was assessed by transcranial color-coded duplex scanning. Results: The dynamics of perfusion control mechanisms (myogenic and neurogenic) have been studied in the young healthy population of Krasnoyarsk. The role of the autonomic nervous system in initiating a particular type of ocular NVR has been identified. The authors have also determined the significance of the nitric oxide production intensity in different types of NVR. Conclusion: The type of ocular NVR is determined by parameters of cerebral hemodynamics. Normotonic NVR is associated with effective autoregulation of cerebral blood flow, while hyper- and hypotonic types of reactions - with autoregulatory failure.
Databáze:	MEDLINE
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