| Autor: |
Thalib L; 1 Department of Public Health, College of Health Sciences, Qatar University, Doha, Qatar., Furuya-Kanamori L; 2 Research School of Population Health, Australian National University, Canberra, ACT, Australia., AlHabib KF; 3 Department of Cardiac Sciences, King Fahad Cardiac Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Alfaleh HF; 3 Department of Cardiac Sciences, King Fahad Cardiac Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia., AlShamiri MQ; 3 Department of Cardiac Sciences, King Fahad Cardiac Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Amin H; 4 Mohammed Bin Khalifa Cardiac Center, Manama, Bahrain., Al Suwaidi J; 5 Department of Cardiology, Hamad Medical Corporation, Doha, Qatar., Sulaiman K; 6 Department of Cardiology, Royal Hospital, Muscat, Oman., Almahmeed W; 7 Heart and Vascular Institute, Cleveland Clinic, Abu Dhabi, United Arab Emirates., Alsheikh-Ali AA; 8 College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.; 9 Institute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.; 10 Institute for Clinical Research and Health Policy Studies, Tufts University School of Medicine, Boston, MA, USA., Al-Motarreb A; 11 Department of Cardiology, Sana'a University, Sana'a, Yemen., Doi SA; 2 Research School of Population Health, Australian National University, Canberra, ACT, Australia.; 12 College of Medicine, Qatar University, Doha, Qatar.; 13 School of Agricultural, Environmental and Computing Sciences, University of Southern Queensland, Toowoomba, Queensland, Australia. |
| Abstrakt: |
Acute coronary syndromes (ACS) are the most common cardiovascular diseases and are associated with a significant risk of mortality and morbidity. The Global Registry of Acute Coronary Events (GRACE) risk score postdischarge is a widely used ACS prediction model for risk of mortality (low, intermediate, and high); however, it has not yet been validated in patients from the Arabian Gulf. This prospective multicenter study (second Gulf Registry of Acute Coronary Events) provides detailed information of the GRACE risk score postdischarge in patients from the Arabian Gulf. Its prognostic utility was validated at 1-year follow-up in over 5000 patients with ACS from 65 hospitals in 6 Arabian Gulf countries (Bahrain, Saudi Arabia, Qatar, Oman, United Arab Emirates, and Yemen). Overall, the goodness of fit (Hosmer and Lemeshow statistic P value = .826), calibration, and discrimination (area under the receiver operating characteristic curve = 0.695; 95% confidence interval: 0.668-0.722) were good. The GRACE risk score postdischarge can be used to stratify 1 year mortality risk in the Arabian Gulf population; it does not require further calibration and has a good discriminatory ability. |
