Efficacy of the Hydroalcoholic Extract of Tribulus terrestris on the Serum Glucose and Lipid Profile of Women With Diabetes Mellitus: A Double-Blind Randomized Placebo-Controlled Clinical Trial.

Autor:	Samani NB; Department of Midwifery, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran., Jokar A; Community Based Psychiatric Care Research Center, Department of Midwifery, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran jokarhs@yahoo.com., Soveid M; Endocrinology and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran., Heydari M; Department of Traditional Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran., Mosavat SH; Research Center for Traditional Medicine and History of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Jazyk:	angličtina
Zdroj:	Journal of evidence-based complementary & alternative medicine [J Evid Based Complementary Altern Med] 2016 Oct; Vol. 21 (4), pp. NP91-7. Date of Electronic Publication: 2016 Jun 02.
DOI:	10.1177/2156587216650775
Abstrakt:	Aim: Considering traditional use of Tribulus terrestris in diabetes and proven antihyperglycemic and antihyperlipidemic effects of T terrestris in animal studies, we aimed to evaluate the efficacy of the hydroalcoholic extract of T terrestris on the serum glucose and lipid profile of women with non-insulin-dependent diabetes mellitus. Methods: Ninety-eight women with diabetes mellitus type 2 were randomly allocated to receive the T terrestris (1000 mg/d) or placebo for 3 months. The patients were evaluated in terms of the fasting blood glucose, 2-hour postprandial glucose, glycosylated hemoglobin, and lipid profile. Results: Tribulus terrestris showed a significant blood glucose-lowering effect in diabetic women compared to placebo (P < .05). Also, the total cholesterol and low-density lipoprotein of T terrestris group was significantly reduced compared with placebo, while no significant effect was observed in the triglyceride and high-density lipoprotein levels. Conclusions: The study showed preliminary promising hypoglycemic effect of T terrestris in women with diabetes mellitus type 2. (© The Author(s) 2016.)
Databáze:	MEDLINE
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