Prediction of Time to Delivery Week-by-Week in Women with a Triplet Pregnancy.

Autor: van de Mheen L; Department of Obstetrics and Gynecology, VU University Medical Center, Amsterdam, The Netherlands., Ravelli AC; Department of Medical Informatics, Academic Medical Center, Amsterdam, The Netherlands., Oudijk MA; Department of Obstetrics and Gynecology, Academic Medical Center, Amsterdam, The Netherlands., Bijvank SN; Department of Obstetrics and Gynecology, Isala Clinics, Zwolle, The Netherlands., Porath MM; Department of Obstetrics and Gynecology, Maxima Medical Center, Veldhoven, The Netherlands., Duvekot JJ; Department of Obstetrics and Gynecology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands., Scholtenhuis MA; Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Bloemenkamp KW; Department of Obstetrics and Gynecology, University Medical Center Utrecht, Utrecht, The Netherlands., Scheepers HC; Department of Obstetrics and Gynecology, Maastricht University Medical Center, Maastricht, The Netherlands., Woiski M; Department of Obstetrics and Gynecology, Radboud University Medical Center, Nijmegen, The Netherlands., van Pampus MG; Department of Obstetrics and Gynecology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands., Groot CJ; Department of Obstetrics and Gynecology, VU University Medical Center, Amsterdam, The Netherlands., Pajkrt E; Department of Obstetrics and Gynecology, Academic Medical Center, Amsterdam, The Netherlands., Mol BW; School of Paediatrics and Reproductive Health, The Robinson Institute, Adelaide, Australia.
Jazyk: angličtina
Zdroj: American journal of perinatology [Am J Perinatol] 2016 Dec; Vol. 33 (14), pp. 1394-1400. Date of Electronic Publication: 2016 May 11.
DOI: 10.1055/s-0036-1583190
Abstrakt: Objective  Some clinicians advise prophylactic administration of antenatal steroids for fetal lung maturation in women with a triplet pregnancy. However, the effect of corticosteroids is limited to 10 to 14 days after administration. The aim of this study was to assess the natural course of triplet pregnancies to allow a better anticipation for administration of corticosteroids. Study Design  We collected data on all triplet pregnancies in the Netherlands from 1999 to 2007 from the Netherlands Perinatal Registration. We calculated time to delivery, the risk of delivery in 2-week intervals at different gestational ages, and the time frame between hospital admission and delivery of the first child. Results  Median gestational age at delivery of 494 women with a triplet pregnancy was 33 +4 weeks (interquartile range of 31-35 +1 weeks). Twenty-one women (4.3%) delivered between 22 and 24 weeks and 146 women (29.6%) delivered before 32 weeks. At a gestational age of 24 weeks, the chance to deliver within the next week was 0.6%. For 26, 28, 30, 31, and 32 weeks, these risks were 2.4, 2.5, 8.1, 7, and 16.7%, respectively. Conclusion  Before 32 weeks of gestation, prophylactic administration of steroids is not indicated as the risk to deliver within 7 days is < 10%.
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Databáze: MEDLINE