3T MRI investigation of cardiac left ventricular structure and function in a UK population: The tayside screening for the prevention of cardiac events (TASCFORCE) study.

Autor: Gandy SJ; NHS Tayside Clinical Radiology, Ninewells Hospital, Dundee, UK.; NHS Tayside Medical Physics, Ninewells Hospital, Dundee, UK., Lambert M; University of Dundee School of Medicine, Dundee, UK., Belch J; University of Dundee School of Medicine, Dundee, UK., Cavin I; NHS Tayside Medical Physics, Ninewells Hospital, Dundee, UK., Crowe E; NHS Tayside Clinical Radiology, Ninewells Hospital, Dundee, UK., Littleford R; University of Dundee School of Medicine, Dundee, UK., MacFarlane JA; NHS Tayside Medical Physics, Ninewells Hospital, Dundee, UK., Matthew SZ; University of Dundee School of Medicine, Dundee, UK., Martin P; NHS Tayside Clinical Radiology, Ninewells Hospital, Dundee, UK., Nicholas RS; NHS Tayside Clinical Radiology, Ninewells Hospital, Dundee, UK.; NHS Tayside Medical Physics, Ninewells Hospital, Dundee, UK., Struthers A; University of Dundee School of Medicine, Dundee, UK., Sullivan F; Department of Family and Community Medicine, University of Toronto, Toronto, Canada.; Department of Research and Innovation, North York General Hospital, Toronto, Canada., Waugh SA; NHS Tayside Medical Physics, Ninewells Hospital, Dundee, UK., White RD; NHS Tayside Clinical Radiology, Ninewells Hospital, Dundee, UK.; Department of Clinical Radiology, University Hospital of Wales, UK., Weir-McCall JR; University of Dundee School of Medicine, Dundee, UK., Houston JG; NHS Tayside Clinical Radiology, Ninewells Hospital, Dundee, UK. ghouston@nhs.net.; University of Dundee School of Medicine, Dundee, UK. ghouston@nhs.net.
Jazyk: angličtina
Zdroj: Journal of magnetic resonance imaging : JMRI [J Magn Reson Imaging] 2016 Nov; Vol. 44 (5), pp. 1186-1196. Date of Electronic Publication: 2016 May 03.
DOI: 10.1002/jmri.25267
Abstrakt: Purpose: To scan a volunteer population using 3.0T magnetic resonance imaging (MRI). MRI of the left ventricular (LV) structure and function in healthy volunteers has been reported extensively at 1.5T.
Materials and Methods: A population of 1528 volunteers was scanned. A standardized approach was taken to acquire steady-state free precession (SSFP) LV data in the short-axis plane, and images were quantified using commercial software. Six observers undertook the segmentation analysis.
Results: Mean values (±standard deviation, SD) were: ejection fraction (EF) = 69 ± 6%, end diastolic volume index (EDVI) = 71 ± 13 ml/m 2 , end systolic volume index (ESVI) = 22 ± 7 ml/m 2 , stroke volume index (SVI) = 49 ± 8 ml/m 2 , and LV mass index (LVMI) = 55 ± 12 g/m 2 . The mean EF was slightly larger for females (69%) than for males (68%), but all other variables were smaller for females (EDVI 68v77 ml/m 2 , ESVI 21v25 ml/m 2 , SVI 46v52 ml/m 2 , LVMI 49v64 g/m 2 , all P < 0.05). The mean LV volume data mostly decreased with each age decade (EDVI males: -2.9 ± 1.3 ml/m 2 , females: -3.1 ± 0.8 ml/m 2 ; ESVI males: -1.3 ± 0.7 ml/m 2 , females: -1.7 ± 0.5 ml/m 2 ; SVI males: -1.7 ± 0.9 ml/m 2 , females: -1.4 ± 0.6 ml/m 2 ; LVMI males: -1.6 ± 1.1 g/m 2 , females: -0.2 ± 0.6 g/m 2 ) but the mean EF was virtually stable in males (0.6 ± 0.6%) and rose slightly in females (1.2 ± 0.5%) with age.
Conclusion: LV reference ranges are provided in this population-based MR study at 3.0T. The variables are similar to those described at 1.5T, including variations with age and gender. These data may help to support future population-based MR research studies that involve the use of 3.0T MRI scanners. J. Magn. Reson. Imaging 2016;44:1186-1196.
(© 2016 The Authors Journal of Magnetic Resonance Imaging published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.)
Databáze: MEDLINE
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