Assessment of In Vitro Biological Activities of Anthocyanins-Rich Plant Species Based on Plinia cauliflora Study Model.

Autor: Pitz HS; Plant Morphogenesis and Biochemistry Laboratory, Natural Products Core, Federal University of Santa Catarina, 1346, 401 Road., PO Box 476, 88040-900, Florianópolis, Santa Catarina State, Brazil., Trevisan AC; Plant Morphogenesis and Biochemistry Laboratory, Natural Products Core, Federal University of Santa Catarina, 1346, 401 Road., PO Box 476, 88040-900, Florianópolis, Santa Catarina State, Brazil., Cardoso FR; Plant Morphogenesis and Biochemistry Laboratory, Natural Products Core, Federal University of Santa Catarina, 1346, 401 Road., PO Box 476, 88040-900, Florianópolis, Santa Catarina State, Brazil., Pereira A; Plant Morphogenesis and Biochemistry Laboratory, Natural Products Core, Federal University of Santa Catarina, 1346, 401 Road., PO Box 476, 88040-900, Florianópolis, Santa Catarina State, Brazil., Moreira EL; Nanoscoping Solutions in Nanotechnology, 250, Vitor Lima Street, 88040-400, Florianópolis, Santa Catarina State, Brazil., de Prá MA; Plant Morphogenesis and Biochemistry Laboratory, Natural Products Core, Federal University of Santa Catarina, 1346, 401 Road., PO Box 476, 88040-900, Florianópolis, Santa Catarina State, Brazil.; Nanoscoping Solutions in Nanotechnology, 250, Vitor Lima Street, 88040-400, Florianópolis, Santa Catarina State, Brazil., Mazzarino L; Plant Morphogenesis and Biochemistry Laboratory, Natural Products Core, Federal University of Santa Catarina, 1346, 401 Road., PO Box 476, 88040-900, Florianópolis, Santa Catarina State, Brazil.; Nanoscoping Solutions in Nanotechnology, 250, Vitor Lima Street, 88040-400, Florianópolis, Santa Catarina State, Brazil., Veleirinho MB; Plant Morphogenesis and Biochemistry Laboratory, Natural Products Core, Federal University of Santa Catarina, 1346, 401 Road., PO Box 476, 88040-900, Florianópolis, Santa Catarina State, Brazil.; Nanoscoping Solutions in Nanotechnology, 250, Vitor Lima Street, 88040-400, Florianópolis, Santa Catarina State, Brazil., Yunes RA; Plant Morphogenesis and Biochemistry Laboratory, Natural Products Core, Federal University of Santa Catarina, 1346, 401 Road., PO Box 476, 88040-900, Florianópolis, Santa Catarina State, Brazil., do Valle RM; Plant Morphogenesis and Biochemistry Laboratory, Natural Products Core, Federal University of Santa Catarina, 1346, 401 Road., PO Box 476, 88040-900, Florianópolis, Santa Catarina State, Brazil., Maraschin M; Plant Morphogenesis and Biochemistry Laboratory, Natural Products Core, Federal University of Santa Catarina, 1346, 401 Road., PO Box 476, 88040-900, Florianópolis, Santa Catarina State, Brazil. m.maraschin@ufsc.br.
Jazyk: angličtina
Zdroj: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2016; Vol. 1391, pp. 65-80.
DOI: 10.1007/978-1-4939-3332-7_5
Abstrakt: Plinia cauliflora (jaboticaba) is a native fruit tree from Brazilian rainforest widely used in popular medicine to prevent diarrhea, asthma, and infections. Studies have shown that the major therapeutic potential of jaboticaba fruits is on its peel, a rich source of anthocyanins. These secondary metabolites have well-known antioxidant and anti-inflammatory activities and have been claimed to be effective to treat diabetes, cancer, cardiovascular diseases, and stroke. This chapter describes a series of methodologies to evaluate important in vitro biological activities like cytotoxicity, proliferation, and migration of a hydroalcoholic extract of jaboticaba peel on mouse fibroblast L929 line. Assays to assess total phenolic, flavonoid, and anthocyanin contents and antioxidant activities are described as well.
Databáze: MEDLINE
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