The challenge of Propionibacterium acnes and revision shoulder arthroplasty: a review of current diagnostic options.

Autor: Shields MV; Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA., Abdullah L; Drexel University College of Medicine, Philadelphia, PA, USA., Namdari S; Rothman Institute Department of Orthopaedics, Thomas Jefferson University Hospital, Philadelphia, PA, USA. Electronic address: surena.namdari@rothmaninstitute.com.
Jazyk: angličtina
Zdroj: Journal of shoulder and elbow surgery [J Shoulder Elbow Surg] 2016 Jun; Vol. 25 (6), pp. 1034-40. Date of Electronic Publication: 2016 Mar 30.
DOI: 10.1016/j.jse.2016.01.009
Abstrakt: Background: Propionibacterium acnes is the most common cause of infection after shoulder arthroplasty. Whereas there are several methods that can aid in the diagnosis of P. acnes infection, there is not a single "gold standard" because of the difficulties inherent in identifying this bacterium. We present an evidence-based discussion of the demographic, clinical, and radiographic predictors of P. acnes infection and review the current options for diagnosis.
Methods: This review was written after a comprehensive analysis of the current literature related to shoulder periprosthetic joint infection and P. acnes identification.
Results and Conclusions: Of the techniques reviewed, α-defensin had the highest sensitivity in detecting P. acnes infection (63%). C-reactive protein level and erythrocyte sedimentation rate were often normal in cases of infection. Whereas P. acnes can be challenging to successfully diagnose, there are several options that are considered preferable because of their higher sensitivities and specificities. The current gold standard is intraoperative culture, but major advances in molecular techniques may provide future improvements in diagnostic accuracy.
(Copyright © 2016 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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