An International Multicenter Study Assessing the Role of Ethnicity on Variation of Lumbar Facet Joint Orientation and the Occurrence of Degenerative Spondylolisthesis in Asia Pacific: A Study from the AOSpine Asia Pacific Research Collaboration Consortium.

Autor: Williams R; Department of Orthopaedics, Princess Alexandra Hospital, Brisbane, Australia., Cheung JP; Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong, SAR, China., Goss B; Department of Orthopaedics, Princess Alexandra Hospital, Brisbane, Australia., Rajasekaran S; Department of Orthopaedics, Ganga Hospital, Coimbatore, India., Kawaguchi Y; Department of Orthopaedic Surgery, University of Toyama, Toyama, Japan., Acharya S; Department of Orthopedics, Sir Gangaram Hospital, New Delhi, India., Kawakami M; Spine Care Center, Wakayama Medical University, Kihoku Hospital, Ito-gun, Japan., Satoh S; Department of Spine Surgery, Eniwa Hospital, Hokkaido, Japan., Chen WJ; Department of Orthopaedic, Chang Gung Memorial Hospital, Taoyuan, Taiwan., Park CK; Department of Neurosurgery, Catholic University of Korea, Seoul, South Korea., Lee CS; Department of Orthopedic Surgery, Sungkyunkwan University School of Medicine, Seoul, South Korea., Foocharoen T; Department of Orthopaedic Surgery, Khonkaen Regional Hospital, Khonkean, Thailand., Nagashima H; Department of Orthopedic Surgery, Tottori University, Yonago, Japan., Kuh S; Department of Neurosurgery, Gangnam Severance Hospital, Seoul, South Korea., Zheng Z; Department of Spine Surgery, The First Hospital Affiliated of Zhongshan University, Guangzhou, China., Condor R; Department of Orthopedics, Cebu Orthopaedic Institute, Cebu, Philippines., Ito M; Department of Advanced Medicine for Spine and Spinal Cord Disorders, Hokkaido University Graduate School of Medicine, Sapporo, Japan., Iwasaki M; Department of Orthopaedic Surgery, Osaka Rosai Hospital, Osaka, Japan., Jeong JH; Department of Neurosurgery, College of Medicine, Soon Chun Hyang Unviersity Bucheon Hospital, Bucheon, South Korea., Luk KD; Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong, SAR, China., Prijambodo B; Department of Orthopaedics and Traumatology, Faculty of Medicine Airlargga University, Surabaya, Indonesia., Rege A; Department of Orthopaedics, Deenanath Mangeshkar Hospital, Jehangir Hospital, Pune, India., Jahng TA; Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam, South Korea., Luo Z; Department of Orthopaedic Surgery, The Fourth Military Medical University, Xi'an, China., Tassanawipas W; Department of Orthopedics, Phramongkuthklao Army Hospital, Bangkok, Thailand., Acharya N; Dwaraka Institute of Spine Care, Bellary, India., Pokharel R; Department of Orthopedics and Trauma Surgery, Tribhuvan University, Kathmandu, Nepal., Shen Y; Department of Spine Surgery, The Third Hospital of Hebei Medical University of China, Shijiazhuang, China., Ito T; Department of Orthopaedic Surgery, Niigata City General Hospital, Niigata, Japan., Zhang Z; Department of Orthopaedic Surgery, Aviation General Hospital, Beijing, China., Aithala P J; Kasturba Medical College, Manipal University, Mangalore, India., Kumar GV; Department of Neurosurgery, Fortis Hospital, Kolkata, India., Jabir RA; Department of Orthopaedic and Traumatology, University of Indonesia / RS Ciptomangunkusumo, Jakarta, Indonesia., Basu S; Division of Neurosciences, Park Clinic, Kolkata, India., Li B; Department of Spine Surgery, The Third Hospital of Hebei Medical University of China, Shijiazhuang, China., Moudgil V; Department of Orthopedic, Punjab Institute of Medical Sciences Jalandhar, Jalandhar, India., Sham P; Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong, SAR, China., Samartzis D; Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong, SAR, China.
Jazyk: angličtina
Zdroj: Global spine journal [Global Spine J] 2016 Feb; Vol. 6 (1), pp. 35-45. Date of Electronic Publication: 2015 Jul 16.
DOI: 10.1055/s-0035-1555655
Abstrakt: Study Design A multinational, multiethnic, cross-sectional image-based study was performed in 33 institutions, representing 10 countries, which were part of the AOSpine Asia Pacific Research Collaboration Consortium. Objective Lumbar facet joint orientation has been reported to be associated with the development of degenerative spondylolisthesis (DS). The role of ethnicity regarding facet joint orientation remains uncertain. As such, the following study was performed across a wide-ranging population base to assess the role of ethnicity in facet joint orientation in patients with DS in the Asia Pacific region. Methods Lateral standing X-rays and axial magnetic resonance imaging scans were obtained for patients with lumbar DS. The DS parameters and facet joint angulations were assessed from L3-S1. Sex, age, body mass index (BMI), and ethnicity were also noted. Results The study included 371 patients with known ethnic origin (mean age: 62.0 years; 64% males, 36% females). The mean BMI was 25.6 kg/m(2). The level of DS was most prevalent at L4-L5 (74.7%). There were 28.8% Indian, 28.6% Japanese, 18.1% Chinese, 8.6% Korean, 6.5% Thai, 4.9% Caucasian, 2.7% Filipino, and 1.9% Malay patients. Variations in facet joint angulations were noted from L3 to S1 and between patients with and without DS (p < 0.05). No differences were noted with regards to sex and overall BMI to facet joint angulations (p > 0.05); however, increasing age was found to increase the degree of angulation throughout the lumbar spine (p < 0.05). Accounting for age and the presence or absence of DS at each level, no statistically significant differences between ethnicity and degree of facet joint angulations from L3-L5 were noted (p > 0.05). Ethnic variations were noted in non-DS L5-S1 facet joint angulations, predominantly between Caucasian, Chinese, and Indian ethnicities (p < 0.05). Conclusions This study is the first to suggest that ethnicity may not play a role in facet joint orientation in the majority of cases of DS in the Asia-Pacific region. Findings from this study may facilitate future comparative studies in other multiethnic populations. An understanding of ethnic variability may assist in identifying those patients at risk of postsurgical development or progression of DS. This study also serves as a model for large-scale multicenter studies across different ethnic groups and cultural boundaries in Asia.
Databáze: MEDLINE