Megakaryoblastic transformation of chronic granulocytic leukaemia. An electron microscopy and cytochemial study.

Autor: Bain B, Catovsky D, O'Brien M, Spiers AS, Richards GH
Jazyk: angličtina
Zdroj: Journal of clinical pathology [J Clin Pathol] 1977 Mar; Vol. 30 (3), pp. 235-42.
DOI: 10.1136/jcp.30.3.235
Abstrakt: Morphological, cytochemical, and ultrastructural electron microscopic (EM) studies were performed on blood and bone-marrow cells of case of Ph1-positive chronic ganulocytic leukaemia in megakaryocytic acute transformation. The entire leukaemic cell population was found to consist and of megakaryoblasts and megakaryocytes. Intermediate stages of maturation between blasts and micromegakaryocytes were observed at EM level.
Databáze: MEDLINE