Archaic RDA Methodology for Vitamin C.
| Autor: | Hickey S; a Newlyn Research Group , Newlyn , Cornwall , England., Schuitemaker G; b Ortho Institute , Gendringen , Netherlands., Yanagisawa A; c Japanese College of IV Therapy , Tokyo , Japan., Noriega L; d Staffordshire University , Stafford , England., González MJ; e University of Puerto Rico, Medical Sciences Campus , San Juan , PR , USA., Miranda-Massari JR; f University of Puerto Rico , San Juan , PR , USA., Chibelushi C; d Staffordshire University , Stafford , England., Downing D; g British Society for Ecological Medicine , London , England. |
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| Jazyk: | angličtina |
| Zdroj: | Critical reviews in food science and nutrition [Crit Rev Food Sci Nutr] 2015 Oct 29, pp. . Date of Electronic Publication: 2015 Oct 29. |
| DOI: | 10.1080/10408398.2012.747486 |
| Abstrakt: | Frei et al's 2012 review entitled "Authors' Perspective: What is the Optimum Intake of Vitamin C in Humans" is both flawed and misleading. RCTs are ill suited to determining the RDA, it is debatable that there is sufficient scientific evidence to determine the optimum intake of vitamin C in humans, observations regarding high-doses of ascorbate have been ignored, and there are inaccuracies of fact with respect to the saturation of blood plasma following low dose intake. Until the limitations of current knowledge are recognised it is unwise to set limits on the dose. |
| Databáze: | MEDLINE |
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