FlyBase: establishing a Gene Group resource for Drosophila melanogaster.

Autor:	Attrill H; Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK., Falls K; The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA., Goodman JL; Department of Biology, Indiana University, Bloomington, IN 47405, USA., Millburn GH; Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK., Antonazzo G; Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK., Rey AJ; Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK., Marygold SJ; Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK sjm41@cam.ac.uk.
Jazyk:	angličtina
Zdroj:	Nucleic acids research [Nucleic Acids Res] 2016 Jan 04; Vol. 44 (D1), pp. D786-92. Date of Electronic Publication: 2015 Oct 13.
DOI:	10.1093/nar/gkv1046
Abstrakt:	Many publications describe sets of genes or gene products that share a common biology. For example, genome-wide studies and phylogenetic analyses identify genes related in sequence; high-throughput genetic and molecular screens reveal functionally related gene products; and advanced proteomic methods can determine the subunit composition of multi-protein complexes. It is useful for such gene collections to be presented as discrete lists within the appropriate Model Organism Database (MOD) so that researchers can readily access these data alongside other relevant information. To this end, FlyBase (flybase.org), the MOD for Drosophila melanogaster, has established a 'Gene Group' resource: high-quality sets of genes derived from the published literature and organized into individual report pages. To facilitate further analyses, Gene Group Reports also include convenient download and analysis options, together with links to equivalent gene groups at other databases. This new resource will enable researchers with diverse backgrounds and interests to easily view and analyse acknowledged D. melanogaster gene sets and compare them with those of other species. (© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.)
Databáze:	MEDLINE
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