Distinctive Characteristic Features of Intramedullary Hemangiopericytomas.

Autor: Türk CÇ; Department of Neurosurgery, Ministry of Health, Antalya Education and Research Hospital, Antalya, Turkey., Kara NN; Department of Neurosurgery, Ministry of Health, Antalya Education and Research Hospital, Antalya, Turkey., Süren D; Department of Pathology, Ministry of Health, Antalya Education and Research Hospital, Antalya, Turkey., Özdöl Ç; Department of Neurosurgery, Ministry of Health, Antalya Education and Research Hospital, Antalya, Turkey., Gediz T; Department of Neurosurgery, Ministry of Health, Antalya Education and Research Hospital, Antalya, Turkey., Yıldız S; Department of Radiology, Ministry of Health, Antalya Education and Research Hospital, Antalya, Turkey.
Jazyk: angličtina
Zdroj: Asian spine journal [Asian Spine J] 2015 Aug; Vol. 9 (4), pp. 522-8. Date of Electronic Publication: 2015 Jul 28.
DOI: 10.4184/asj.2015.9.4.522
Abstrakt: Study Design: The retrospective analysis of intramedullary hemangiopericytomas (HPCs) was performed, and the entity was discussed in accordance with the literature findings.
Purpose: This study aimed at defining distinctive characteristic features of intramedullary HPC with respect to surgical approach and prognosis.
Overview of Literature: Intramedullary HPCs are extremely rare tumors. They originate from capillary pericytes, supposedly follow the vessels over the spinal cord, and infiltrate deep into the spinal cord without a distinct plane. Their treatments and prognosis are not well-defined in the literature.
Methods: Our database was retrospectively reviewed for the cases of HPCs. Later on, a literature search was performed to reveal all reported cases of intramedullary HPCs. The following key words were searched in PubMed databases: "hemangiopericytoma and intramedullary," "hemangiopericytoma and spine (spinal) and intradural," and "hemangiopericytoma and spinal cord." The articles were reviewed for patients' demographics features, imaging characteristics, tumor-specific factors (surgical technique, pathological descriptions, and world health organization grades), and postoperative course and prognosis (adjuvant therapies, recurrences, complications, and mortalities).
Results: A total of seven patients (three male and four female) was reached, with their ages ranging from 15 to 80 years (mean, 32.5 years). The tumors were located majorly in thoracic region (5/7, 71.4%), and only two cases were in the cervical region (2/7, 28.6%). All tumors were completely removed, and only two cases received radiotherapy. No recurrence was reported.
Conclusions: Complete resection of the intramedullary HPCs seems to be the best management strategy for long-term and recurrence-free survival and in alleviating further need for radiotherapy.
Databáze: MEDLINE
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