Hemophagocytic lymphohistiocytosis in children with visceral leishmaniasis.

Autor:	Blázquez-Gamero D; From the *Pediatric Infectious Diseases and Immunodeficiencies Unit, 12 de Octubre University Hospital, Madrid, Spain; †Pediatric Hematology/Oncology Unit, 12 de Octubre University Hospital, Madrid, Spain; ‡WHO Collaborating Centre for Leishmaniasis, Servicio de Parasitología, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain; §Department of Pediatrics, Fuenlabrada University Hospital, Fuenlabrada, Spain; ¶Pediatric Infectious Diseases Unit, Hospital Infantil Universitario Niño Jesús, Madrid, Spain; ‖Department of Pediatrics, Severo Ochoa University Hospital, Leganés, Spain; **Department of Pediatrics, Getafe University Hospital, Getafe, Spain; ††Department of Pediatrics, Móstoles University Hospital, Móstoles, Spain; and ‡‡Department of Pediatrics, Ramón y Cajal University Hospital, Madrid, Spain., Domínguez-Pinilla N, Chicharro C, Negreira S, Galán P, Pérez-Gorricho B, Calvo C, Prieto L, De la Parte M, Otheo E, Vivanco JL, Ruiz-Contreras J
Jazyk:	angličtina
Zdroj:	The Pediatric infectious disease journal [Pediatr Infect Dis J] 2015 Jun; Vol. 34 (6), pp. 667-9.
DOI:	10.1097/INF.0000000000000685
Abstrakt:	Acquired hemophagocytic lymphohistiocitosis (HLH) syndrome can be a complication of visceral leishmaniasis (VL). A multicenter prospective study was conducted to determine the frequency of HLH syndrome in children with VL. Twenty-four children with VL were identified, and 10 (41%) developed HLH syndrome. VL should be ruled out in all children with HLH criteria living in or coming from endemic areas.
Databáze:	MEDLINE
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