| Autor: |
Tsygankov MA, Zobnina AE, Padkina MV |
| Jazyk: |
ruština |
| Zdroj: |
Prikladnaia biokhimiia i mikrobiologiia [Prikl Biokhim Mikrobiol] 2014 Jul-Aug; Vol. 50 (4), pp. 429-36. |
| DOI: |
10.7868/s055510991404028x |
| Abstrakt: |
Genes encoding truncated versions of bovine and chicken gamma interferon genes lacking predicted protease cleavage sites at the C-terminus were constructed and expressed in the yeast Pichia Pastoris. The recombinant proteins possessed increased stability in comparison with the corresponding wild-type gamma interferons while retaining biological activity. The recombinant strains provide a useful tool for the purification of bovine and chicken gamma interferons for their use in veterinary applications. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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