Detection of Mycobacterium tuberculosis by EasyNAT diagnostic kit in sputum samples from Tanzania.

Autor: Mhimbira FA; Ifakara Health Institute, Bagamoyo, Tanzania fmhimbira@ihi.or.tz., Bholla M; Ifakara Health Institute, Bagamoyo, Tanzania Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland., Sasamalo M; Ifakara Health Institute, Bagamoyo, Tanzania., Mukurasi W; Ifakara Health Institute, Bagamoyo, Tanzania., Hella JJ; Ifakara Health Institute, Bagamoyo, Tanzania., Jugheli L; Ifakara Health Institute, Bagamoyo, Tanzania Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland., Reither K; Ifakara Health Institute, Bagamoyo, Tanzania Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland.
Jazyk: angličtina
Zdroj: Journal of clinical microbiology [J Clin Microbiol] 2015 Apr; Vol. 53 (4), pp. 1342-4. Date of Electronic Publication: 2015 Jan 21.
DOI: 10.1128/JCM.03037-14
Abstrakt: The EasyNAT assay was evaluated for the detection of tuberculosis in sputum smears from presumptive pulmonary tuberculosis (TB) patients in an African high-TB and high-HIV setting. The sensitivity of the EasyNAT assay was 66.7%, and the specificity and positive predictive value were 100% for the culture-positive patients. The sensitivity was only 10% in the smear-negative and culture-positive patients.
(Copyright © 2015, American Society for Microbiology. All Rights Reserved.)
Databáze: MEDLINE