Autor: |
Chum HH; Office of Laboratory Animal Care, University of California Berkeley, Berkeley, California, USA. hchum@berkeley.edu., Long CT; Department of Laboratory Animal Resources, North Carolina State University, Raleigh, North Carolina, USA., McKeon GP; Department of Laboratory Animal Resources, North Carolina State University, Raleigh, North Carolina, USA., Chang AG; Department of Comparative Medicine, Stanford University, Stanford, California, USA., Luong RH; Department of Comparative Medicine, Stanford University, Stanford, California, USA., Albertelli MA; Department of Comparative Medicine, Stanford University, Stanford, California, USA. |
Jazyk: |
angličtina |
Zdroj: |
Comparative medicine [Comp Med] 2014 Oct; Vol. 64 (5), pp. 404-8. |
Abstrakt: |
An 10-y-old, intact male rhesus macaque (Macaca mulatta) presented for bilateral scrotal swelling and a distended abdomen. A soft mass in the left upper quadrant of the abdomen was palpated. A barium study did not reveal any gastrointestinal abnormalities. Exploratory laparotomy revealed a large (1.25 kg, 15.0 × 13.0 × 9.5 cm), red and tan, soft, circumscribed, spherical mass within the greater omentum and 10 to 20 smaller (diameter, 1 to 4 cm), soft to firm masses in the mesentery and greater omentum. The resected mass was a self-strangulating abdominal lipoma, a pedunculated neoplasm composed of white adipocytes arising from peritoneal adipose tissue undergoing secondary coagulation necrosis after strangulation of the blood supply due to twisting of the mass around the peduncle. The smaller masses were histologically consistent with simple or self-strangulating pedunculated abdominal lipomas. The macaque presented again 9 mo later with a firm, 5.0-cm mass in the midabdomen, with intestinal displacement visible on radiographs. Given this animal's medical history and questionable prognosis, euthanasia was elected. Necropsy revealed numerous, multifocal to coalescing, 1.0- to 15.0-cm, pale tan to yellow, circumscribed, soft to firm, spherical to ellipsoid, pedunculated masses that were scattered throughout the mesentery, greater omentum, lesser omentum, and serosal surfaces of the gastrointestinal tract. All of the masses were pedunculated abdominal lipomas, and most demonstrated coagulation necrosis due to self-strangulation of the blood supply. To our knowledge, this report is the first to describe abdominal lipomatosis with secondary self-strangulation of masses in a rhesus macaque. |
Databáze: |
MEDLINE |
Externí odkaz: |
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