Role of insulin resistance in uric acid nephrolithiasis.

Autor:	Li H; Hanhan Li, Dane E Klett, Raymond Littleton, Jack S Elder, Jesse D Sammon, VUI Center for Outcomes Research Analytics and Evaluation, Henry Ford Health System, Detroit, MI 48202, United States., Klett DE; Hanhan Li, Dane E Klett, Raymond Littleton, Jack S Elder, Jesse D Sammon, VUI Center for Outcomes Research Analytics and Evaluation, Henry Ford Health System, Detroit, MI 48202, United States., Littleton R; Hanhan Li, Dane E Klett, Raymond Littleton, Jack S Elder, Jesse D Sammon, VUI Center for Outcomes Research Analytics and Evaluation, Henry Ford Health System, Detroit, MI 48202, United States., Elder JS; Hanhan Li, Dane E Klett, Raymond Littleton, Jack S Elder, Jesse D Sammon, VUI Center for Outcomes Research Analytics and Evaluation, Henry Ford Health System, Detroit, MI 48202, United States., Sammon JD; Hanhan Li, Dane E Klett, Raymond Littleton, Jack S Elder, Jesse D Sammon, VUI Center for Outcomes Research Analytics and Evaluation, Henry Ford Health System, Detroit, MI 48202, United States.
Jazyk:	angličtina
Zdroj:	World journal of nephrology [World J Nephrol] 2014 Nov 06; Vol. 3 (4), pp. 237-42.
DOI:	10.5527/wjn.v3.i4.237
Abstrakt:	Metabolic syndrome has been implicated in the pathogenesis of uric acid stones. Although not completely understood, its role is supported by many studies demonstrating increased prevalence of uric acid stones in patients with metabolic syndrome and in particular insulin resistance, a major component of metabolic syndrome. This review presents epidemiologic studies demonstrating the association between metabolic syndrome and nephrolithiasis in general as well as the relationship between insulin resistance and uric acid stone formation, in particular. We also review studies that explore the pathophysiologic relationship between insulin resistance and uric acid nephrolithiasis.
Databáze:	MEDLINE
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