The relationship between fragmented QRS complexes and SYNTAX and Gensini scores in patients with acute coronary syndrome.

Autor: Bekler A; Department of Cardiology, Canakkale Onsekiz Mart University, School of Medicine, Canakkale, Turkey. adembekler27@gmail.com., Barutçu A, Tenekecioglu E, Altun B, Gazi E, Temiz A, Kırılmaz B, Ozkan MT, Yener AU
Jazyk: angličtina
Zdroj: Kardiologia polska [Kardiol Pol] 2015; Vol. 73 (4), pp. 246-54. Date of Electronic Publication: 2014 Nov 05.
DOI: 10.5603/KP.a2014.0208
Abstrakt: Background: Fragmented QRS (fQRS) complexes on 12-lead electrocardiography (ECG) have been reported to be predictors of cardiac events and all-cause mortality in coronary artery disease (CAD).
Aim: To investigate the relationship between fQRS complexes and SYNTAX and Gensini scores in patients with acute coronary syndrome (ACS).
Methods: A total of 302 patients (223 men and 79 women) with ACS (133 ST elevated myocardial infarction [STEMI], 107 non-STEMI [NSTEMI], and 62 unstable angina pectoris [USAP]) were evaluated retrospectively in this study. An fQRS pattern was found in 70 patients (fQRS group) but was not found in 232 patients (non-fQRS group). SYNTAX score > 22 and Gensini score > 20 were defined as high SYNTAX and Gensini scores. The relationship between the presence of fQRS on 12-lead ECG and SYNTAX and Gensini scores was assessed.
Results: SYNTAX score (p < 0.001), Gensini score (p < 0.001), NYHA class (p < 0.001), QRS duration (p < 0.001), number of disease vessels (p = 0.003), and high sensitive troponin T levels (p = 0.026) were significantly higher in the fQRS group. The number of fQRS leads (HR 5.79, 95% CI 2.78-12.06, p < 0.001, HR 3.41, 95% CI 1.32-8.78, p = 0.016, respectively) was found to be an independent predictor of high SYNTAX score and high Gensini score in multivariate analysis.
Conclusions: The number of fQRS leads on 12-lead ECG on admission is associated with the severity and complexity of CAD in patients with ACS.
Databáze: MEDLINE
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