| Autor: |
Sariev AK, Abaimov DA, Tankevich MV, Prokhorov DI, Adekenov SM, Arystan LI, Seĭfulla RD |
| Jazyk: |
ruština |
| Zdroj: |
Eksperimental'naia i klinicheskaia farmakologiia [Eksp Klin Farmakol] 2014; Vol. 77 (8), pp. 39-44. |
| Abstrakt: |
We have experimentally studied pathways of elimination of an oximized derivative of phytoflavonoid pinostrobine by HPLC/mass spectrometry. Four potential metabolites of pinostrobine oxime have been found and there was an attempt to determine their molecular structures on the basis of their fragmentation under positive electrospray ionization conditions. It is established that pinostrobine oxime is removed from the organism mainly unchanged and also in the form of glucuronated derivative. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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