Recent insights into the pathophysiology of omental metastases.
Autor: | Koppe MJ; Department of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands; Department of Surgery, Ghent University Hospital, Ghent, Belgium., Nagtegaal ID, de Wilt JH, Ceelen WP |
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Jazyk: | angličtina |
Zdroj: | Journal of surgical oncology [J Surg Oncol] 2014 Nov; Vol. 110 (6), pp. 670-5. Date of Electronic Publication: 2014 Jun 24. |
DOI: | 10.1002/jso.23681 |
Abstrakt: | Although, useful in inflammatory conditions, the greater omentum represents an important site of metastasis in peritoneal carcinomatosis and is therefore frequently removed as a staging or therapeutic tool. Apart from the milky spots, omental adipose stem cells, and adipocytes have recently been identified to play a role in the preferential homing of tumor cells to the omentum. The extent of omentectomy and whether a routine omentectomy should be done are still known unknowns. (© 2014 Wiley Periodicals, Inc.) |
Databáze: | MEDLINE |
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