First trimester coffee and tea intake and risk of gestational diabetes mellitus: a study within a national birth cohort.

Autor: Hinkle SN; Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA., Laughon SK, Catov JM, Olsen J, Bech BH
Jazyk: angličtina
Zdroj: BJOG : an international journal of obstetrics and gynaecology [BJOG] 2015 Feb; Vol. 122 (3), pp. 420-8. Date of Electronic Publication: 2014 Jun 20.
DOI: 10.1111/1471-0528.12930
Abstrakt: Objective: Coffee and tea consumption is associated with a decreased type 2 diabetes risk in non-pregnant adults. We examined the relation between first trimester coffee and tea consumption and gestational diabetes mellitus (GDM) risk.
Design: Population-based cohort study.
Setting: Denmark 1996-2002.
Population: Non-diabetic women with singleton pregnancies in the Danish National Birth Cohort (n = 71,239).
Methods: Estimated adjusted relative risks (RR) and 95% confidence intervals (95%CI) for the association between first trimester coffee and tea or estimated total caffeine and GDM.
Main Outcome Measures: GDM ascertained from the National Hospital Discharge Register or maternal interview.
Results: Coffee or tea intake was reported in 81.2% (n = 57,882) and 1.3% (n = 912) of pregnancies were complicated by GDM. Among non-consumers, 1.5% of pregnancies were complicated by GDM. Among coffee drinkers, GDM was highest among women who drank ≥8 cups/day (1.8%) with no significant difference across intake levels (P = 0.10). Among tea drinkers, there was no difference in GDM across intake levels (1.2%; P = 0.98). After adjustment for age, socio-occupational status, parity, pre-pregnancy body mass index, smoking, and cola, there was suggestion of a protective, but non-significant association with increasing coffee (RR ≥8 versus 0 cups/day = 0.89 [95%CI 0.64-1.25]) and tea (RR ≥8 versus 0 cups/day = 0.77 [95%CI 0.55-1.08]). Results were similar by smoking status, except a non-significant 1.45-fold increased risk with ≥8 coffee cups/day for non-smokers. There was a non-significant reduced GDM risk with increasing total caffeine.
Conclusions: Our results suggest that moderate first trimester coffee and tea intake were not associated with GDM increased risk and possibly may have a protective effect.
(© 2014 Royal College of Obstetricians and Gynaecologists.)
Databáze: MEDLINE
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