The bright side of transposons in crop evolution.
| Autor: | Vitte C, Fustier MA, Alix K, Tenaillon MI |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Briefings in functional genomics [Brief Funct Genomics] 2014 Jul; Vol. 13 (4), pp. 276-95. Date of Electronic Publication: 2014 Mar 27. |
| DOI: | 10.1093/bfgp/elu002 |
| Abstrakt: | The past decades have revealed an unexpected yet prominent role of so-called 'junk DNA' in the regulation of gene expression, thereby challenging our view of the mechanisms underlying phenotypic evolution. In particular, several mechanisms through which transposable elements (TEs) participate in functional genome diversity have been depicted, bringing to light the 'TEs bright side'. However, the relative contribution of those mechanisms and, more generally, the importance of TE-based polymorphisms on past and present phenotypic variation in crops species remain poorly understood. Here, we review current knowledge on both issues, and discuss how analyses of massively parallel sequencing data combined with statistical methodologies and functional validations will help unravelling the impact of TEs on crop evolution in a near future. (© The Author 2014. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.) |
| Databáze: | MEDLINE |
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