Autor: |
Sung M; Department of Child and Adolescent Psychiatry, Institute of Mental Health, Singapore., Chin CH; Department of Child and Adolescent Psychiatry, Institute of Mental Health, Singapore., Lim CG; Department of Child and Adolescent Psychiatry, Institute of Mental Health, Singapore., Liew HS; Department of Child and Adolescent Psychiatry, Institute of Mental Health, Singapore., Lim CS; Department of Psychological Medicine, Khoo Teck Puat Hospital, Singapore., Kashala E; Department of Child and Adolescent Psychiatry, Institute of Mental Health, Singapore., Weng SJ; Department of Child and Adolescent Psychiatry, Institute of Mental Health, Singapore. |
Abstrakt: |
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder with both core symptoms and associated symptoms (eg, irritability, aggression, and comorbidities) that affect both the individual and the family/systems around them. There have been recent advances in the understanding of the underlying pathophysiology of ASD pertaining to genetics, epigenetics, neurological, hormonal, and environmental factors that contribute to the difficulties found in individuals with ASD. With this improved understanding, there has been a shift in the application of psychopharmacology in ASD and its related disorders. A literature review was conducted to examine research published in the last 5 years between different classes of psychotropic medications and ASD. The broad scope of the existing literature for the use of conventional medications is summarized and novel medications are discussed. |