[Anemia as a surgical risk factor].

Autor: Moral García V; Servicio de Anestesiología, Clínica del Dolor, Hospital Universitario de la Santa Creu i Sant Pau, Barcelona, España. Electronic address: vmoralg@santpau.cat., Ángeles Gil de Bernabé Sala M, Nadia Diana K, Pericas BC, Nebot AG
Jazyk: Spanish; Castilian
Zdroj: Medicina clinica [Med Clin (Barc)] 2013 Jul; Vol. 141 Suppl 1, pp. 47-54.
DOI: 10.1016/S0025-7753(13)70053-8
Abstrakt: Perioperative anemia is common in patients undergoing surgery and is associated with increased morbidity and mortality and a decreased quality of life. The main causes of anemia in the perioperative context are iron deficiency and chronic inflammation. Anemia can be aggravated by blood loss during surgery, and is most commonly treated with allogeneic transfusion. Moreover, blood transfusions are not without risks, once again increasing patient morbidity and mortality. Given these concerns, we propose to review the pathophysiology of anemia in the surgical environment, as well as its treatment through the consumption of iron-rich foods and by oral or intravenous iron therapy (iron sucrose and iron carboxymaltose). In chronic inflammatory anemia, we use erythropoiesis-stimulating agents (erythropoietin alpha) and, in cases of mixed anemia, the combination of both treatments. The objective is always to reduce the need for perioperative transfusions and speed the recovery from postoperative anemia, as well as decrease the patient morbidity and mortality rate.
(Copyright © 2013 Elsevier España, S.L. All rights reserved.)
Databáze: MEDLINE