[Detoxification of patients with GHB dependence].

Autor: de Weert-van Oene GH, Schellekens AF, Dijkstra BA, Kamal R, de Jong CA
Jazyk: Dutch; Flemish
Zdroj: Tijdschrift voor psychiatrie [Tijdschr Psychiatr] 2013; Vol. 55 (11), pp. 885-90.
Abstrakt: Background: A new detoxification method for GHB dependence was developed recently in the Netherlands. The method involves the use of pharmaceutical GHB.
Aim: To describe the characteristics of GHB dependent inpatients, the course of the detoxification process and patients' progress in the three months following inpatient detoxification.
Method: 229 GHB dependent patients were monitored during and after inpatient detoxification. Records were kept of the psychiatric symptoms, withdrawal symptoms and relapses.
Results: The average age of the patients was 29 years; 69% of the patients were male. They reported severe symptoms of co-occurring depression and anxiety. Detoxification was successful in 86% of the patients and, on a whole, the procedure ran smoothly, without complications. However, within three months following detoxification two-thirds of the patients had relapsed and were again taking GHB.
Conclusion: Pharmaceutical GHB can be used as an alternative to the benzodiazepine method for detoxifying patients with GHB dependence. However, the high relapse rates following detoxification are of great concern.
Databáze: MEDLINE