[Relationship between maternal milk and serum thyroid hormones in patients with thyroid related diseases].

Autor:	Zhang Q; Department of Endocrinology, PUMC Hospital, Beijing, China., Lian XL, Chai XF, Bai Y, Dai WX
Jazyk:	čínština
Zdroj:	Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae [Zhongguo Yi Xue Ke Xue Yuan Xue Bao] 2013 Aug; Vol. 35 (4), pp. 427-31.
DOI:	10.3881/j.issn.1000-503X.2013.04.013
Abstrakt:	Objective: To explore the relationship between maternal milk and serum thyroid hormones in patients with thyroid-related diseases. Methods: Serum and breast milk samples were collected from 56 breastfeeding mothers. Milk and serum free triiodothyronine (FT3), free thyroxine (FT4), triiodothyronine(T3), thyroxine (T4), and thyrotrophin (TSH) were determined, and T3/T4 was calculated. Using the serum thyroid hormones as the independent variables and milk thyroid hormones as the dependent variables, we performed linear regression analysis. Results: The milk FT3, FT4, T3, T4, TSH, and T3/T4 were (2.30 ± 0.82) pg/ml ,(0.45 ± 0.26) ng/dl, (0.35 ± 0.20) ng/ml, (2.96 ± 1.55) Μg/dl, (0.12 ± 0.08) ΜU/ml, and 0.12 ± 0.04, respectively. Milk FT3 (r = 0.778, P = 0.000), T3 (r = 0.603, P = 0.000), T4 (r = 0.485, P = 0.004), and TSH (r = 0.605, P = 0.000) concentrations were positively correlated with those in serum. Conclusion: Thyroid hormones are present in human milk and are positively correlated with those in serum.
Databáze:	MEDLINE
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