| Autor: |
Siqueira-Batista R, Gomes AP, Mendonça EG, Vitorino RR, Azevedo SF, Freitas Rde B, Santana LA, Oliveira MG |
| Jazyk: |
English; Portuguese |
| Zdroj: |
Revista Brasileira de terapia intensiva [Rev Bras Ter Intensiva] 2012 Dec; Vol. 24 (4), pp. 394-400. |
| DOI: |
10.1590/s0103-507x2012000400017 |
| Abstrakt: |
Despite advances in treatment and campaigns for prevention and control of malaria on the various continents where it is still rampant, this disease remains significantly relevant to the contemporary world. Plasmodium falciparum is the organism that is mainly responsible for severe malaria, which is characterized by disturbances in different organs and systems, with possibly fatal outcomes. Although incipient, proteomic studies of malaria have yielded favorable prospects for elucidating the biological aspects of Plasmodium as well as the pathophysiological, diagnostic, prophylactic, and therapeutic mechanisms of the disease. Thus, the aim of the present article is to present a brief review of the applications of proteomic analysis in P. falciparum malaria. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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