The greasy response to virus infections.

Autor: Tanner LB; Department of Biochemistry, Yong Loo Lin School of Medicine and NUS Graduate School for Integrative Sciences and Engineering (NGS), National University of Singapore, Singapore 117456, Singapore., Lee B
Jazyk: angličtina
Zdroj: Cell host & microbe [Cell Host Microbe] 2013 Apr 17; Vol. 13 (4), pp. 375-7.
DOI: 10.1016/j.chom.2013.04.002
Abstrakt: Virus replication requires lipid metabolism, but how lipids mediate virus infection remains obscure. In this issue, Amini-Bavil-Olyaee et al. (2013) reveal that IFITM proteins disturb cholesterol homeostasis to block virus entry. Previously, in Cell, Morita and colleagues (2013) showed the antiviral potency of the lipid mediator protectin D1.
(Copyright © 2013 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE