SWItching on epidermal cell fate.
| Autor: | Perdigoto CN; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Bardot ES, Ezhkova E |
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| Jazyk: | angličtina |
| Zdroj: | Cell stem cell [Cell Stem Cell] 2013 Feb 07; Vol. 12 (2), pp. 141-2. |
| DOI: | 10.1016/j.stem.2013.01.011 |
| Abstrakt: | Chromatin regulatory complexes are well known regulators of stem cell fate; however, the mechanisms regulating their activity are not well understood. In this issue of Cell Stem Cell, Bao et al. (2013) show that ACTL6a inhibits targeting of the SWI/SNF complex to differentiation genes, thereby preserving the epidermal progenitor state. (Copyright © 2013 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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