| Autor: |
Słupecka M; The Kielanowski Institute of Animal Physiology & Nutrition, Polish Academy of Sciences, 05-110 Jablonna, Poland., Woliński J, Prykhodko O, Ochniewicz P, Gruijc D, Fedkiv O, Weström BR, Pierzynowski SG |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of animal science [J Anim Sci] 2012 Dec; Vol. 90 Suppl 4, pp. 311-4. |
| DOI: |
10.2527/jas.53921 |
| Abstrakt: |
Use of nutritional components from the milk and eventually from the solid feed relates to the growth and development of gastrointestinal tract (GIT). We studied the effect of pancreatic-like enzymes [porcine pancreatic enzymes (Creon) or microbial-derived amylase, protease, and lipase] on GIT morphology and lipid absorption in suckling piglets. Both enzyme preparations, in low or high dose, were fed via a stomach tube twice a day for 7 d starting at 8 d of age and controls received vehicle, n = 6. The day after treatments ended, lipid absorption was tested after which pigs were euthanized and GIT was examined. Enzyme cocktails, irrespective of their origin, increased (P < 0.001) triglyceride level in blood. Enzyme preparation affected (P < 0.001) small intestinal mucosal thickness, villi length, and crypt depth and (P < 0.01) mitotic division of enterocytes. In addition, the external administration of pancreatic enzymes stimulated pancreatic growth as observed by increased (P < 0.05) mitotic division of pancreatic cells. The study revealed that pancreatic or pancreatic-like enzymes of microbial origin administrated in the early postperinatal period enhance GIT development and may be used to better prepare the GIT of piglets for milk use and weaning. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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